Zulfiqar Malik

Inhibition of Calcium Signaling Affects Phagosome Maturation and Intracellular Survival of M. Tuberculosis
Biography

Malik ZA, Iyer SS, Kusner DJ. Mycobacterium tuberculosis phagosomes exhibit altered calmodulin-dependent signal transduction: contribution to inhibition of phagosome-lysosome fusion and intracellular survival in human macrophages. J Immunol. 2001 Mar 1;166(5):3392-401. PubMed PMID: 11207296.

Malik ZA, Thompson CR, Hashimi S, Porter B, Iyer SS, Kusner DJ. Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase. J Immunol. 2003 Mar 15;170(6):2811-5. PubMed PMID: 12626530.

Myung PS, Clements JL, White DW, Malik ZA, Cowdery JS, Allen LH, Harty JT, Kusner DJ, Koretzky GA. In vitro and in vivo macrophage function can occur independently of SLP-76. Int Immunol. 2000 Jun;12(6):887-97. PubMed PMID:10837416.

Malik ZA, Denning GM, Kusner DJ. Inhibition of Ca(2+) signaling by Mycobacterium tuberculosis is associated with reduced phagosome-lysosome fusion and increased survival within human macrophages. J Exp Med. 2000 Jan 17;191(2):287-302. PubMed PMID: 10637273; PubMed Central PMCID: PMC2195750.

Chief of Research
New York Cancer and Blood Specialists
Zulfiqar Malik