Malaria remains a global health crisis with billions of people at risk for developing this disease each year.

Our research is focused on understanding how the function of Plasmodium parasite-specific T cells and B cells are regulated during malaria. Our broader goals are to use this information to identify and develop new strategies to improve immunity against this globally important disease.

To achieve our goals, we are performing experiments designed to elucidate the molecular and transcriptional mechanisms that determine how infection, inflammation and immunotherapy impact the formation of long-lived, pathogen-specific memory T and B cell subsets.

As part of our efforts, we also perform comprehensive, comparative studies using models of vaccination, bacterial and viral infection, and we investigate host immunity using related eukaryotic pathogens.