Michael Musci

The Role of SLP-76 and SLAP-130 in the Regulation of T Cell Antigen Receptor Signal Transduction
Biography

Musci MA, Motto DG, Ross SE, Fang N, Koretzky GA. Three domains of SLP-76 are required for its optimal function in a T cell line. J Immunol. 1997 Aug 15;159(4):1639-47. PubMed PMID: 9257823.

Musci MA, Latinis KM, Koretzky GA. Signaling events in T lymphocytes leading to cellular activation or programmed cell death. Clin Immunol Immunopathol. 1997 Jun;83(3):205-22. Review. PubMed PMID: 9175909.

Musci MA, Hendricks-Taylor LR, Motto DG, Paskind M, Kamens J, Turck CW, Koretzky GA. Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases. J Biol Chem. 1997 May 2;272(18):11674-7. PubMed PMID: 9115214.

Musci MA, Beaves SL, Ross SE, Yi T, Koretzky GA. Surface expression of hemopoietic cell phosphatase fails to complement CD45 deficiency and inhibits TCR-mediated signal transduction in a Jurkat T cell clone. J Immunol. 1997 Feb 15;158(4):1565-71. PubMed PMID: 9029091.

Motto DG, Musci MA, Ross SE, Koretzky GA. Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C gamma 1 activation in T cells. Mol Cell Biol. 1996 Jun;16(6):2823-9. PubMed PMID: 8649391; PubMed Central PMCID: PMC231274.

Motto DG, Musci MA, Koretzky GA. Surface expression of a heterologous phosphatase complements CD45 deficiency in a T cell clone. J Exp Med. 1994 Oct 1;180(4):1359-66. PubMed PMID: 7931069; PubMed Central PMCID: PMC2191683.

Hovis RR, Donovan JA, Musci MA, Motto DG, Goldman FD, Ross SE, Koretzky GA. Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45. Science. 1993 Apr 23;260(5107):544-6. PubMed PMID: 8475387.

Hematology/Oncology
Hematology/Oncology
Ironwood Cancer and Research Centers
Michael Musci