Neonatal immunology and immune system development

The Bermick laboratory is interested in how the neonatal immune system develops under normal conditions and after early life inflammatory exposures. Current projects include:
- Longitudinal cytokine/chemokine profiling of serum and stool from premature infants from birth through NICU discharge
- Longitudinal assessment of monocyte function in premature infants from birth through NICU discharge
- Determining how type 1 interferons regulate developmental stage-specific H3K4me3 placement in human monocytes and murine macrophages
- Targeting iron to improve outcomes in a murine model of neonatal Escherichia coli sepsis
- Understanding the impact of a murine model of chorioamnionitis on offspring immune function throughout the lifespan
- Understanding how probiotic supplementation during murine pregnancy and lactation influences offspring immune function