Ajai Dandekar

Advisor
The Role of B Cells and Gamma-Delta T Cells in the Pathogenesis of Mouse Hepatitis Virus Induced Demyelination
Biography

Butler NS, Dandekar AA, Perlman S. Antiviral antibodies are necessary to prevent cytotoxic T-lymphocyte escape in mice infected with a coronavirus. J Virol. 2007 Dec;81(24):13291-8. Epub 2007 Oct 3. PubMed PMID: 17913802; PubMed Central PMCID: PMC2168833.

Perlman S, Dandekar AA. Immunopathogenesis of coronavirus infections: implications for SARS. Nat Rev Immunol. 2005 Dec;5(12):917-27. Review. PubMed PMID: 16322745.

Dandekar AA, O'Malley K, Perlman S. Important roles for gamma interferon and NKG2D in gammadelta T-cell-induced demyelination in T-cell receptor beta-deficient mice infected with a coronavirus. J Virol. 2005 Aug;79(15):9388-96. PubMed PMID: 16014902; PubMed Central PMCID: PMC1181615.

Dandekar AA, Anghelina D, Perlman S. Bystander CD8 T-cell-mediated demyelination is interferon-gamma-dependent in a coronavirus model of multiple sclerosis. Am J Pathol. 2004 Feb;164(2):363-9. PubMed PMID: 14742242; PubMed Central PMCID: PMC1602263.

Dandekar AA, Jacobsen G, Waldschmidt TJ, Perlman S. Antibody-mediated protection against cytotoxic T-cell escape in coronavirus-induced demyelination. J Virol. 2003 Nov;77(22):11867-74. PubMed PMID: 14581523; PubMed Central PMCID:PMC254260.

Dandekar AA, Perlman S. Virus-induced demyelination in nude mice is mediated by gamma delta T cells. Am J Pathol. 2002 Oct;161(4):1255-63. PubMed PMID:12368199; PubMed Central PMCID: PMC1867296.

Wu GF, Dandekar AA, Pewe L, Perlman S. The role of CD4 and CD8 T cells in MHV-JHM-induced demyelination. Adv Exp Med Biol. 2001;494:341-7. PubMed PMID:11774490.

Dandekar AA, Wu GF, Pewe L, Perlman S. Axonal damage is T cell mediated and occurs concomitantly with demyelination in mice infected with a neurotropic coronavirus. J Virol. 2001 Jul;75(13):6115-20. PubMed PMID: 11390613; PubMed Central PMCID: PMC114327.

Wu GF, Dandekar AA, Pewe L, Perlman S. CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination. J Immunol. 2000 Aug 15;165(4):2278-86. PubMed PMID: 10925317.

Associate Professor
Division of Pulmonary, Critical Care and Sleep Medicine
University of Washington
Ajai Dandekar