Zachary Kraus

Advisor
TRAF5: A Key Positive Regulator of Lymphocyte Activation
Biography

Arcipowski KM, Stunz LL, Graham JP, Kraus ZJ, Vanden Bush TJ, Bishop GA. Molecular mechanisms of TNFR-associated factor 6 (TRAF6) utilization by the oncogenic viral mimic of CD40, latent membrane protein 1 (LMP1). J Biol Chem. 2011 Mar 25;286(12):9948-55. Epub 2011 Jan 24. PubMed PMID: 21262968; PubMed Central PMCID: PMC3060549.

Xie P, Kraus ZJ, Stunz LL, Liu Y, Bishop GA. TNF receptor-associated factor 3 is required for T cell-mediated immunity and TCR/CD28 signaling. J Immunol. 2011 Jan 1;186(1):143-55. Epub 2010 Nov 17. PubMed PMID: 21084666; PubMed Central PMCID: PMC3044490.

Kraus ZJ, Nakano H, Bishop GA. TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17140-5. Epub 2009 Sep 17. PubMed PMID:19805155; PubMed Central PMCID: PMC2761366.

Kraus ZJ, Haring JS, Bishop GA. TNF receptor-associated factor 5 is required for optimal T cell expansion and survival in response to infection. J Immunol. 2008 Dec 1;181(11):7800-9. PubMed PMID: 19017969; PubMed Central PMCID:PMC2636746.

Xie P, Kraus ZJ, Stunz LL, Bishop GA. Roles of TRAF molecules in B lymphocyte function. Cytokine Growth Factor Rev. 2008 Jun-Aug;19(3-4):199-207. Epub 2008 May 21. Review. PubMed PMID: 18499506; PubMed Central PMCID: PMC2495079.

Bishop GA, Moore CR, Xie P, Stunz LL, Kraus ZJ. TRAF proteins in CD40 signaling. Adv Exp Med Biol. 2007;597:131-51. Review. PubMed PMID: 17633023.
 

Senior Staff Scientist
CDER/OBP
U.S. Food and Drug Administration
Zachary Kraus