Immunology Graduate Program

Molecular and Cellular Biology of the Immune System

John  Graham

M.S., Cell and Molecular Biology, Eastern Michigan University
B.S., Biology, Hillsdale College
 
Contact Information
     Email: john-graham@uiowa.edu
     Phone: 335-7816
     Campus Address: 2219 MERF
Start date in program: 2006
Mentor: Gail Bishop
Research Interests
My research focuses on the Epstein-Barr virus encoded CD40 mimic Latent membrane protein 1 (LMP1). Specifically, I am interested in how the TRAF binding site, through regulation of the TNF receptor associated factor (TRAF) adaptor signaling molecules, TRAF3&5, regulates some but not all LMP1 signaling outcomes.
Publications
Graham , J. P., Moore, C. R. and Bishop, G. A. Roles of the TNF receptor-associated factor (TRAF)2/3 binding site in differential B cell signaling by CD40 and its viral oncogenic mimic, latent membrane protein 1 (LMP1). J. Immunol. Sept.;183:2966-2973, 2009.